Pseudo‐continuous arterial spin labeling technique for measuring CBF dynamics with high temporal resolution

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Pseudo-continuous arterial spin labeling technique for measuring CBF dynamics with high temporal resolution.

Cerebral blood flow (CBF) can be measured noninvasively with nuclear magnetic resonance (NMR) by using arterial water as an endogenous perfusion tracer. However, the arterial spin labeling (ASL) techniques suffer from poor temporal resolution due to the need to wait for the exchange of labeled arterial spins with tissue spins to produce contrast. In this work, a new ASL technique is introduced,...

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Quantifying CBF with arterial spin labeling.

The basic principles of measuring cerebral blood flow (CBF) using arterial spin labeling (ASL) are reviewed. The measurement is modeled by treating the ASL method as a magnetic resonance imaging (MRI) version of a microsphere study, rather than a diffusible tracer study. This approach, particularly when applied to pulsed ASL (PASL) experiments, clarifies that absolute calibration of CBF primari...

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A new signal-to-noise ratio (SNR) efficient method is introduced for the mapping of vascular territories based on pseudocontinuous arterial spin labeling (ASL). A pseudocontinuous tagging pulse train is modified using additional transverse gradient pulses and phase cycling to place some arteries in a tag condition, while others passing through the same tagging plane are in a control condition. ...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 1999

ISSN: 0740-3194,1522-2594

DOI: 10.1002/(sici)1522-2594(199909)42:3<425::aid-mrm3>3.3.co;2-j